The latest odds for Manny Pacquiao's May 7 fight with "Sugar" Shane Mosley differ on the money lines, but all the books are in agreement: If you want to win on Manny this weekend, you're going to have to put down the big bucks.
Let's compare this to other recent Pacquiao fights. In November, Bodog had Pacquiao at -450 to beat Antonio Margarito, so he's roughly two times as heavy a favorite against Mosley than against Margarito.
The odds were similar, though, for Pacquiao's fight last March against Joshua Clottey. Pacquiao was -800 for that one, with Clottey at +500. Pacquiao blew through Clottey, who mostly stood still over 12 rounds of "action" in the first-ever main event fight at Cowboys Stadium.
In November 2009 against Miguel Cotto, Pacquiao was about a -300 favorite against the Puerto Rican. His fight with Ricky Hatton (May 2009) saw Pacquiao favored between -240 and -300. The last time Manny was not the favorite was against Oscar de la Hoya in 2008. Manny was a +150 or so underdog by the time that fight actually happened, as the line steadily moved back toward even money after early lines had Oscar as a pretty sturdy favorite.
Last year against Floyd Mayweather Jr., Mosley was a +250 underdog, while Mayweather was about a -350 favorite.